My pick would be my Stainless Ruger Security Six with a 4" barrel. I carried it as a duty weapon for years, until the powers that be forced me to retire it in favor of a tactical tupperware Glock. BLAH. Anyway, like the GP100 (I have the 1st gen with the heavy frame GP100) its well built. But its not quite as heavy and handles much better. The trigger is better also. Plus its plenty strong. I put thousands of rounds of hot reloaded .357 ammo thru the gun, and its still tight. When I say hot I mean 158jhp sitting on...well...lets say MUCH more powder than is listed today in the Speer manual. I used to use the Speer #8, and well....with the load of Blue Dot it listed, the muzzle blast is/was of biblical proportions. Anyway, its still my favorite sidearm.