CO Bigelow in the village is wonderful too. Perhaps its inventory pales in comparison to Pasteurs, but it is a beautiful and incredibly important shop all the same.
1. 53 East 34th St., b/w Park and Madison ((212) 683-3838)
2. 806 Lexington Ave., b/w 62nd and 63rd ((212) 838-2500)
I live and work within walking distance of both stores. They are fantastic. However, I generally frequent the 34th Street location simply because there is more room to maneuver around the store.
Pasteur, Aedes De Venustas, Cambridge Chemists, CO Bigelow, The Bathroom, MiN, Osswald, Santa Maria Novella.....Those are pretty much my favorite shops. I'm a born and raised Manhattanite, 34 years.