Sorry, absolutely no experience with silicone, only with 2-part epoxy.
Me neither, but I'm considering going with silicone on the 2 I'm getting ready to set because from what I've heard you get most of the permanence of epoxy without having to drill out the knots to replace them. Quarters are just easier than finding and cutting cork, and it seems like with something like silicone, they would actually be easier to remove than cork.