Movie set in South Africa.
Bingo! Connected from the previous film by Ryan Reynolds. Bullock won her oscar in the based-on-the-true-story The Blindside, and Steenburgen won hers for based-on-some-kind-of-story Melvin and Howard. Of course, supporting cast Mr. Incredible Craig T. Nelson and Golden Girl Betty White. You are up!The Proposal
Good guess, but no spouse involved with RDJ's character. Pre-dates this movie by a bit as well.
Majority of One
... note: I am unclear if you intend a movie where the "undercover" aspect is part of the story in the film or not.