I am also thinking of giving the 41 a try. I have the long handle Progress and my other razor was long handle 23C... deliberating between getting the standard R41 or the grande.
From reading the entire combined R41 thread, it appears many went with the standard to begin with and found it performed better with an aftermarket, heavier handle. This is why Muhle came out with the Grande. If you have another typical modern DE, ie Muhle, Edwin Jagger or even some vintage Gillettes, those threads are the same. What do I mean? I'd go with the Grande for a larger option and if you don't like it you should be able to use one of your other handles on it. If you do like it, you may find your other razors work better with the Grande handle as well. Options are good! My $.02.
BTW, I ordered the Grande. I'd also encourage to read through that R41 combined thread...lots of knowledge and experience to learn from.