Other considerations in choosing a cartridge for long range shooting is barrel life, recoil, amount of powder burned if you are a reloader, and kinetic energy needed down range at the target. . . .
On a hot wildcat, I figure a dollar a shot for the barrel. A top shelf barrel, chambered and installed, will run you about a grand. Most of the hot wildcats (22-6mm, and 6mm-284 to name two) will pretty much roast a barrel in 1000 shots, and that is if you are really careful with them. There are various ways to deal with recoil. Barrel life is another matter entirely.